Artesunate 99% CAS 88495-63-0 Artemisia annua extract

Product Informations

Artesunate is made from the effective component artemisinin extracted from Artemisia annua, which is unique in China, through chemical synthesis. It mainly acts on the red phase clones of malaria parasites. It is the only effective derivative of artemisinin that can be made into water-soluble preparations at present. It can kill the Plasmodium in the erythrocytic phase and achieve the antimalarial effect.  It has the characteristics of high antimalarial activity, rapid antipyretic, short time for the negative transformation of Plasmodium, and small toxic and side effects. It is the first choice for the treatment of severe malaria.
1、 Plant origin
Artesunate is a semi synthetic artesunate derivative.
2、 Mechanism of action
The mechanism of action of artesunate artemisinin. It first acts on the food vesicle membrane, surface membrane and mitochondria of Plasmodium. The second is nuclear membrane and endoplasmic reticulum. In addition, it also has a certain impact on the chromatin in the nucleus. As this product first acts on the food bubble membrane, thus blocking the nutrient intake, the malaria parasite quickly starves of amino acids, rapidly forms autophagic vesicles, and is continuously discharged from the body, losing a large amount of cytoplasm and dies.
3、 Role
1. Antiparasitic drugs
Artesunate is a commonly used antiparasitic drug. It is a derivative of artesunate with sesquiterpene lactone structure, which is a reduced artesunate.
2. Potential anticancer effects
Artesunate has significant killing effect on tumor cells and is not easy to produce drug resistance. In recent years, scholars at home and abroad have found that artesunate can play an anti-tumor role by inhibiting tumor cell proliferation, inducing tumor cell differentiation and apoptosis, regulating cell signal transduction, inhibiting tumor angiogenesis, inhibiting tumor invasion and metastasis, sensitizing anti-tumor chemotherapy drugs and reversing drug resistance.
4、 Application field
1. Pharmaceutical industry

Product Parameters

COMPANY PROFILE
Product Name	Artesunate
CAS	88495-63-0
Chemical Formula	C19H28O8
Brand	Hande
Manufacturer	Yunnan Hande Bio-Tech Co., Ltd.
Country	Kunming, China
Established	1993
BASIC INFORMATION
Synonyms	ARTENSUNATE;Butanedioicacid,1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]ester;Artesunate(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-Chemicalbook1,2-benzodioxepin-10-olhydrogensuccinate;ARTESUNATE;ArtesunateC19H28O8;Artemisininmonosuccinate;ArtesunicAcid;ButanedioicAcidMono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]Ester
Structure
Weight	384.42
HS Code	N/A
Quality Specification	Company Specification
Certificates	N/A
Assay	Customized according to customer needs
Appearance	White crystal
Method of Extraction	Artemisia annua Linn.
Annual Capability	Customized according to customer needs
Package	Customized according to customer needs
Test Method	HPLC
Logistics	Multiple transports
Payment Terms	T/T, D/P, D/A
Other	Accept customer audit all the time; Assist clients with regulatory registration.

1.All products sold by the company are semi-finished raw materials. The products are mainly aimed at manufacturers with production qualifications, and raw materials are not final products.
2.The potential efficacy and applications involved in the introduction are all from the published literature. Individuals do not recommend direct use, and individual purchases are refused.
3.The pictures and product information on this website are for reference only, and the actual product shall prevail.

Hande factory: 

Yunnan hande Biotechnology Co., Ltd., founded in August 1993, is a high-tech enterprise specializing in biotechnology research and development. After years of development, hande has established a perfect quality system, controlled the quality of products according to high standards, and maximized the output value of production capacity. Its products have passed the certification of multinational laws and regulations, and become a plant raw material manufacturer that makes everyone feel at ease.