In this high pressure,high rhythm and accelerated flow living environment,some people often delay their sleep time at night,which makes it difficult to fall asleep,resulting in some sleep disorders.What should we do?If there is a problem,there will be a way to solve the problem.
At the moment when many people hear melatonin,they think that melatonin is a beauty product.In fact,melatonin is an internal hormone that induces natural sleep.It overcomes sleep obstacles and improves sleep quality by regulating people’s natural sleep.In the market,it is an increasingly popular health care product to assist sleep.
According to the statistics of the World Health Organization,the global sleep disorder rate is 27%,which has become the second most common mental disorder in the world.Almost one in three people has sleep problems and one in 10 meets the formal diagnostic criteria for insomnia.The report released by the China sleep research association shows that more than 300 million people in China have sleep disorders,while the degree of insomnia in adults is as high as 38.2%.
So can Melatonin really help sleep?What effect does it have?
###Let’s look at melatonin and its role.
Melatonin(MT)is one of the hormones secreted by the pineal gland.Melatonin belongs to indole heterocyclic compounds.Its chemical name is N-acetyl-5 methoxytryptamine,also known as pinealoxin.After melatonin synthesis,it is stored in the pineal gland.Sympathetic excitation innervates pineal gland cells to release melatonin.The secretion of melatonin has an obvious circadian rhythm,which is inhibited during the day and active at night.
Melatonin can inhibit the hypothalamic pituitary gonadal axis,reduce the contents of gonadotropin releasing hormone,gonadotropin,luteinizing hormone and follicular estrogen,and directly act on the gonads to reduce the contents of androgen,estrogen and progesterone.The latest research shows that melatonin is the commander-in-chief of endocrine.It controls the activities of various endocrine glands in the body,thus indirectly controlling the function of our whole body.
Function and Regulation of Melatonin
1)Adjust circadian rhythm
Melatonin secretion has a circadian rhythm.Supplementing melatonin from outside the body can maintain the melatonin level in the body in a young state,adjust and restore the circadian rhythm,not only deepen sleep and improve sleep quality,but also improve the functional state of the whole body,improve the quality of life and delay the process of aging.Because with the growth of age,the pineal gland shrinks until calcification,resulting in the weakening or disappearance of the rhythm of the biological clock.Especially after the age of 35,the melatonin secreted by the body decreases significantly,with an average decrease of 10~15%every 10 years,resulting in sleep disorders and a series of functional disorders.The reduction of melatonin level and sleep loss is one of the important signs of human brain aging.
2)Delayed aging
The pineal gland of the elderly gradually shrinks,and the secretion of MT decreases accordingly.The amount of Mel required by various organs in the body is insufficient,resulting in aging and diseases.Scientists call the pineal gland the body’s aging clock.When we supplement MT from outside,we can turn back the aging clock.
3)Prevent lesions
Because MT can easily enter cells,it can be used to protect nuclear DNA.If DNA is damaged,it may lead to cancer.If there is enough Mel in the blood,it is not easy to get cancer.
4)Regulatory effect on central nervous system
A large number of clinical and experimental studies show that melatonin,as an endogenous neuroendocrine hormone,has direct and indirect physiological regulation on the central nervous system,therapeutic effects on sleep disorders,depression and mental diseases,and protective effects on nerve cells.For example,melatonin has a sedative effect,can also treat depression and psychosis,can protect nerves,can relieve pain,regulate hormones released by hypothalamus and so on.
5)Regulation of immune system
In recent ten years,the regulatory effect of melatonin on the immune system has attracted widespread attention.Studies at home and abroad have shown that melatonin not only affects the growth and development of immune organs,but also regulates humoral immunity,cellular immunity and cytokines.For example,melatonin can regulate cellular and humoral immunity,as well as the activity of a variety of cytokines.
6)Regulatory effect on cardiovascular system
The function of the vascular system has obvious circadian rhythm and seasonal rhythm,including blood pressure,heart rate,cardiac output,renin angiotensin aldosterone,etc.The serum melatonin secretion level can reflect the corresponding time of the day and the corresponding season of the year.In addition,the relevant experimental results confirmed that the increase of MT secretion at night was negatively correlated with the decrease of cardiovascular activity;Pineal melatonin can prevent arrhythmia caused by ischemia-reperfusion injury,affect blood pressure control,regulate cerebral blood flow,and regulate the reactivity of peripheral arteries to norepinephrine.
7)In addition,melatonin also regulates the human respiratory system,digestive system and urinary system.
Suggestion for Melatonin
melatonin is not a drug.It can only play an auxiliary role in insomnia and has no therapeutic effect.For problems such as poor sleep quality and waking up halfway,it will not have a significant improvement effect.In these cases,you should seek medical treatment in time and obtain correct drug treatment.
Want to know more about melatonin?Hande is committed to providing customers with better and healthier extraction products.We provide high-quality and high-standard melatonin products to effectively help you improve your sleep and live efficiently every day!
Post time: May-11-2022