I3C:Anti-cancer substances often present in cruciferous plants such as broccoli

Indole-3-carbinol(I3C)is a well-studied indole substance.More than a decade ago,scientists discovered that indoles and isothiocyanates can inhibit tumor growth in animal models.They can protect cells from DNA damage,fight bacterial and viral infections,and fight inflammation.In a series of big data analysis on Europeans and Americans,European and American people who regularly eat broccoli have a lower risk of prostate cancer than others;people who eat broccoli and other cruciferous vegetables five times a week have a lower risk of lung cancer.

But exactly how indole-3-carbinol plays an anti-cancer effect is what scientists have always wanted to investigate.Through in vitro and in vivo tests,the researchers pointed out that indole-3-carbinol can release the ubiquitination modification of PTEN by WWP1,allowing PTEN to return to the plasma membrane and recruit dimerization,thereby exerting its anticancer function.

Of course,the fact that indole-3-carbinol is effective in inhibiting tumor growth does not mean that broccoli can resist cancer,that is to say,”food contains anti-cancer substances”does not mean”food is anti-cancer”.In the equivalent conversion,it is necessary to eat nearly 6 pounds of cruciferous vegetables every day to achieve the potential anti-cancer effect,which is unlikely for most people.The most important role of this research is to provide a new anti-cancer target,which provides a new direction for the research and development of new anti-cancer targeted drugs,and also provides new hope for cancer patients.

Indole-3-carbinol,this substance is mainly used as organic synthesis intermediate and pharmaceutical intermediate.For the synthesis of antiviral drugs.Need to be stored in an airtight container in a cool,dry place.Store away from oxidizing agents.

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