Factory Supply Natural paclitaxel powder

Short Description:

Natural paclitaxel is a complex secondary metabolite extracted from the bark of taxus chinensis.It is the only known drug that can promote microtubule polymerization and stabilize polymerized microtubules.After the cell contact with paclitaxel,a large number of microtubules will accumulate in the cell,and the accumulation of these microtubules interferes with various functions of the cell,especially the cell division stops in the mitosis period,blocking the normal division of the cell.

Natural paclitaxel has a wide range of medicinal value,it is considered to be a high efficiency,low toxicity,broad spectrum of natural anticancer drugs.Clinically,it is often used to treat malignant tumors such as breast cancer,ovarian cancer,uterine cancer,some head and neck cancer and lung cancer.Its mechanism of action is to prevent the polymerization and depolymerization of tubulin by binding to tubulin,thus inhibiting the mitosis of tumor cells and inducing apoptosis of tumor cells.In addition,paclitaxel can also regulate the activity of anti-apoptotic mediators.

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Product Detail

Product Tags

Product Informations

Name:Paclitaxel

CAS number:33069-62-4

Chemical formula:C47H51NO14

Specifications:99%-102%

Color:white or nearly white powder

Source:Taxus yunnanensis,Taxus chinensis

Type:APIs

Role of natural paclitaxel

1.anti-tumor effect:natural paclitaxel is currently one of the most widely used clinical chemotherapy drugs,can be used to treat breast cancer,ovarian cancer,lung cancer and other malignant tumors.Its mechanism of action is to bind to a specific part of the microtubule of tumor cells,prevent the depolymerization of the original microtubule in the cell,make the microtubule stable,and accumulate a large number of microtubules in the cell.In this way,the tubulin dimer content in the tubulin library of tumor cells does not reach a certain concentration,and tumor cells cannot be rapidly reassembled by tubulin to form spindle microtubules during mitosis,which inhibits cell division and proliferation,and stops cancer cells in G2 and M stages until death,thus preventing the growth of cancer cells.

2.Immunomodulatory effects:Studies have found that natural paclitaxel can enhance the function of the immune system and promote the activation and proliferation of immune cells.This is of great significance for enhancing the body's resistance to disease and improving the immune response.

3,anti-inflammatory effect:natural paclitaxel has a certain anti-inflammatory effect,can inhibit the occurrence and development of inflammatory response.This has certain potential for the treatment of inflammatory diseases,such as rheumatoid arthritis,inflammatory bowel disease,etc.

4.Angiogenesis inhibition:Studies have found that natural paclitaxel can inhibit the angiogenesis process of tumors,thereby blocking the nutrient supply of tumors and limiting their growth and spread.

5.anti-cardiovascular disease effect:natural paclitaxel also has a certain application prospect in the cardiovascular field.Studies have shown that it can inhibit the proliferation of vascular endothelial cells and smooth muscle cells,thereby reducing the occurrence and development of atherosclerosis.

Role of natural paclitaxel

1.Safety: Our natural paclitaxel is derived from natural plants and does not contain any chemical synthetic ingredients, so it has a higher safety profile.

2.Effectiveness: The chemical structure and biological activity of natural paclitaxel make it more effective in cancer treatment.

3.Wide applicability: Natural paclitaxel can be used to treat a variety of cancers, such as lung, breast, ovarian, stomach, etc.

4.Scientific support: Our natural paclitaxel is developed based on the latest scientific research and technology with reliable scientific support.