Product Informations
Grape seed proanthocyanidins(grape seed extract)have strong antioxidant and free radical elimination effects,and can effectively eliminate superoxide anion free radicals and hydroxyl free radicals.It has strong antioxidant activity and has been widely used in food,medicine,cosmetics and other fields.
1.The source of grape seed proanthocyanidins
Seeds of Vitis vinifera.
2.the role of grape seed proanthocyanidins
1.Antioxidant activity
Proanthocyanidins have extremely strong antioxidant activity and are one of the strongest and most effective free radical scavengers discovered by humans so far,especially their in vivo activity.The antioxidant activity of proanthocyanidins exhibits a dose-effect relationship,but if it exceeds a certain concentration,its antioxidant activity will decrease with increasing concentration.Antioxidant characteristics and mechanism:①Effectively remove superoxide anion free radicals and hydroxyl free radicals,etc.,and can also interrupt free radical chain reaction;②Participate in the metabolism of phospholipids and arachidonic acid and protein phosphorylation,and protect lipids from occurring Peroxidative damage;③It is a powerful metal chelator,which can chelate metal ions and form inert compounds in the body;④Protect and stabilize vitamin C,which is helpful for the absorption of vitamin C.
2.Antitumor activity
Proanthocyanidins have a significant killing effect on various tumor cells,and have a significant inhibitory effect on a variety of carcinogens in the initiation and cancer-promoting stages.Proanthocyanidins can inhibit the growth of cancer cells and induce apoptosis.In addition,for liver cancer,prostate cancer,skin cancer,etc.,they all show good anti-cancer activity.With the deepening of research,proanthocyanidins will play a greater role in the prevention and treatment of cancer,and bring benefits to the treatment of cancer.Gospel.
3.Anti-inflammatory,anti-allergic,anti-edema activity
Proanthocyanidins can reduce the increase of capillary permeability caused by inflammatory mediators such as histamine and bradykinin,reduce the fragility of capillary walls,reduce the tension and permeability of capillaries,and protect the material transport ability of capillaries.resulting in anti-inflammatory activity.In addition,proanthocyanidins can also inhibit the activity of histamine decarboxylase,limit the effect of hyaluronidase,and have a significant effect on various arthritis and gastric and duodenal ulcers.
4.Other
Proanthocyanidins also have immunomodulatory activity,anti-radiation,anti-mutation,anti-diarrhea,anti-bacterial and anti-virus,anti-dental caries,improve visual function,prevent senile dementia,and treat sports injuries.
3.Application fields of grape seed proanthocyanidins
1.Health food
At present,the health food(mainly oligomer capsules or tablets)with proanthocyanidins as the main component in the domestic and foreign markets can prevent and treat heart disease,arteriosclerosis,phlebitis,etc.related to free radicals by scavenging oxygen free radicals..Proanthocyanidins can also be used as a natural preservative to extend the shelf life of food and eliminate the food safety risks that synthetic preservatives may bring.Because of its lipid-lowering effect,anti-cancer activity,blood-pressure-lowering effect,etc.,it is widely used in health food such as blood-lowering,blood-lipid-lowering,anti-tumor,and brain-strengthening food,and is also used as an ingredient or additive in ordinary food.
2.Pharmaceutical industry
Grape seed proanthocyanidins were first used in the treatment of hay fever and allergies in the 1960s,and their therapeutic effects on vascular diseases were confirmed in the 1980s with further research.In recent years,grape seed proanthocyanidins have also been used to treat corneal diseases,retinal diseases,and prevent periodontal disease and cancer.It is used in foreign markets for physical therapy of microcirculation diseases(eye and peripheral capillary permeability diseases and venous and lymphatic insufficiency).
3.Cosmetics industry
The antioxidant,free radical scavenging ability,anti-elastase activity and microcirculation improvement activity of proanthocyanidins have opened up a wide range of application prospects in cosmetics.Skin care products containing proanthocyanidins can inhibit the generation of peroxides caused by oxygen free radicals generated by ultraviolet radiation,and have obvious effects on improving skin inflammation,preventing blackening,and anti-aging.At present,night creams,hair lotions,mouthwashes,skin whitening agents,anti-inflammatory agents and oral deodorants made of proanthocyanidins have successively appeared in France,Italy and Japan.
Product Parameters
| COMPANY PROFILE | |
| Product Name | Grape seed proanthocyanidins |
| CAS | 4852-22-6 |
| Chemical Formula | C30H26O13 |
| Brand | Hande |
| Manufacturer | Yunnan Hande Bio-Tech Co., Ltd. |
| Country | Kunming, China |
| Established | 1993 |
| BASIC INFORMATION | |
| Synonyms | Procyanidins;Proanthocyanidins |
| Structure |  |
| Weight | 594.52 |
| HS Code | N/A |
| Quality Specification | Company Specification |
| Certificates | N/A |
| Assay | Customized according to customer needs |
| Appearance | Reddish brown powder |
| Method of Extraction | Grape seeds have the highest content of procyanidins and rich species. |
| Annual Capability | Customized according to customer needs |
| Package | Customized according to customer needs |
| Test Method | TLC |
| Logistics | Multiple transports |
| Payment Terms | T/T, D/P, D/A |
| Other | Accept customer audit all the time; Assist clients with regulatory registration. |
Hande product statement
1.All products sold by the company are semi-finished raw materials. The products are mainly aimed at manufacturers with production qualifications, and raw materials are not final products.
2.The potential efficacy and applications involved in the introduction are all from the published literature. Individuals do not recommend direct use, and individual purchases are refused.
3.The pictures and product information on this website are for reference only, and the actual product shall prevail.
