Does ursolic acid have antitumor effect?

Ursolic acid is a triterpenoid compound found in natural plants, which is extracted from rosemary. It has many biological effects, such as sedation, anti-inflammatory, antibacterial, anti diabetes, anti ulcer, reducing blood glucose, etc. ursolic acid also has obvious antioxidant function. In addition, ursolic acid can also show its anticancer activity by inducing cell apoptosis, inhibiting cell cycle process, inhibiting cell proliferation, inhibiting migration, and reducing tumorigenesis through a variety of signal pathways.
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Does ursolic acid have antitumor effect? At present, experimental studies have shown that ursolic acid inhibits a variety of cancers, including bladder cancer, colon cancer, breast cancer, cervical cancer, gastric cancer, glioma, neuroblastoma, fibrosarcoma, liver cancer, leukemia, multiple myeloma, lung cancer, ovarian cancer, pancreatic cancer, thyroid cancer, melanoma and prostate cancer. In order to further understand and study the effect of ursolic acid on cancer and open a new chapter in chemotherapy, scientists have carried out a variety of in vivo and in vitro studies.
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Post time: Jul-26-2022