Paclitaxel is a natural product isolated and purified from the bark,woody roots,leaves,shoots and seedlings of the redbud tree,with the highest content in the bark.Paclitaxel is mainly used for ovarian and breast cancers,but it is also effective for lung cancer,colorectal cancer,melanoma,head and neck cancer,lymphoma and brain tumor.Let’s take a look at paclitaxel natural anti-cancer drug in the following article.
Paclitaxel is widely used in the treatment of lung cancer,breast cancer,ovarian cancer,head and neck cancer,gastric cancer and other malignant tumors.It can make microtubulin and microtubulin dimer,which constitute microtubules,lose dynamic balance,induce and promote microtubulin polymerization,microtubule assembly and prevent depolymerization,thus stabilizing microtubules and inhibiting mitosis and triggering apoptosis of cancer cells,thus effectively stopping the proliferation of cancer cells and playing an anti-cancer role.
It has been nearly 30 years since paclitaxel was marketed in 1992.Because of its precise efficacy,wide indications and great clinical demand,the research and development of improved dosage forms of paclitaxel has continued,and the paclitaxel dosage forms that have been marketed include common paclitaxel injection,paclitaxel liposome and albumin paclitaxel.The paclitaxel products are currently the top-ranked chemical agents in China in terms of sales amount,and also the largest in terms of sales amount in the field of antitumor drugs.
Note:The potential efficacy and applications described in this article are from published literature.
Post time: Jun-13-2023