Paclitaxel is a diterpenoid alkaloid with anticancer activity, which can be extracted from taxaceae plants. It has complex novel chemical structure, extensive and significant biological activity, new and unique mechanism of action and scarce natural resources.
The production difficulty of paclitaxel mainly comes from the following aspects:
1, lack of resources: Taxaceae plant resources themselves are very poor, and slow growth, which makes the acquisition and extraction of paclitaxel very difficult.
2, the extraction and separation process is complex: the extraction of paclitaxel from taxaceae plants needs to go through multiple steps, including plant collection, extraction, separation, purification, etc., which requires highly professional technology and equipment.
3, the chemical synthesis is difficult: although the chemical synthesis method of paclitaxel has made some progress, but its synthesis path is long, the synthesis steps are many, the need to use expensive chemical reagents, and the reaction conditions are difficult to control, the yield is low, not suitable for industrial production.
Therefore, in order to solve the production problems of paclitaxel, it is necessary to increase the investment in scientific and technological research and development, explore new extraction and synthesis methods, and improve the yield and extraction efficiency. At the same time, it is also necessary to protect wild taxus resources and promote artificial cultivation to meet the growing market demand.
Note: The potential benefits and applications presented in this article are derived from the published literature.
Yunnan Hande Biotechnology Co., Ltd. has been focused on the production of paclitaxel for 26 years, and is an independent manufacturer of plant-extracted anti-cancer drug paclitaxel API approved by the United States FDA, European EDQM, Australia TGA, China CFDA, India, Japan and other national regulatory agencies. Yunnan Hande paclitaxel, spot supply, factory direct sales, welcome to inquire, 18187887160 (WhatsApp the same number)
Post time: Oct-10-2023