Hot Selling API CAS 700-06-1 Indole-3-Carbinol 99% Powder

Product Informations

Name:Indole-3-carbinol

Nickname:indole-3-methane

CAS No.:700-06-1

Chemical formula:C9H9NO

Molecular structure:

Specification:99%HPLC

Color:white powder

The Effect of Indole-3-carbinol

1. Anti-hormone-like activity: Indole-3-methanol can affect the metabolic pathway of estrogen, increase the activity of estradiol 2-hydroxylase and the metabolic level of catechol pathway, and thus increase the level of 2-hydroxy-estrone of hormones. It can also reduce the stimulation of female glands by reducing the 16α-hydroxy-estrogen pathway, exerting anti-hormone-like activity and inhibiting certain estrogen-dependent tumors.

2. Inhibit the binding of carcinogens to DNA: Indole-3-methanol can prevent aflatoxin AFB1 from binding to DNA, inhibit the mutation-inducing effect of AFB1 on organisms, and also inhibit the binding of DNA adducts related to carcinogens in cigarette smoke.

3. Regulate metabolic enzyme activity in the body: Indole-3-methanol can induce the activity of drug metabolizing enzymes in Phase I and Phase II, increase the activity of glutathione in tissues and target organs, transcriptionally induce the activities of glutathione S-transferase (GST), epoxide hydrolase and quinone oxidoreductase NAD (P) H, and participate in the detoxification of electrophiles. Protects cells from oxidative damage and plays an anticancer role.

4. in the prevention of cancer: oral indole-3-methanol can help prevent several cancers, including breast cancer, uterine cancer, prostate cancer and rectal cancer.

5. support for liver function: indole-3-methanol has a certain protective effect on the liver.

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